In To read or not to read: a neurophysiological study, we report a study case about a patient with pure alexia,
in whom event-related potentials (ERPs) revealed a delay in the P100 component and an absent N170 compared to controls.
Thi suggests that in this patient case the alexia might result from deficits in visual perception which leads to an
inability to activate the VWFA.
To read or not to read: a neurophysiological study
Pure alexia (PA) has been associated with visual deficits or a failure to activate the visual word form area (VWFA).
We report a patient with pure alexia due to posterior cortical atrophy, in whom event-related potentials revealed a delay in the P100
component and an absent N170 compared with controls. Furthermore, there was a tendency for a larger delay in P100 latencies associated
with incorrectly read words. This suggests that some cases of PA might result from deficits in visual perception, signaled by the P100
early potential which could lead to an inability to consistently activate the VWFA, marked by the absent N170.